First-Step Mutations for Adaptation at Elevated Temperature Increase Capsid Stability in a Virus

The relationship between mutation, protein stability and protein function plays a central role in molecular evolution. Mutations tend to be destabilizing, including those that would confer novel functions such as host-switching or antibiotic resistance. Elevated temperature may play an important rol...

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Detalles Bibliográficos
Autores principales: Lee, Kuo Hao, Miller, Craig R., Nagel, Anna C., Wichman, Holly A., Joyce, Paul, Ytreberg, F. Marty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183071/
https://www.ncbi.nlm.nih.gov/pubmed/21980515
http://dx.doi.org/10.1371/journal.pone.0025640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183071/
https://www.ncbi.nlm.nih.gov/pubmed/21980515
http://dx.doi.org/10.1371/journal.pone.0025640

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