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Inter-Allelic Prion Propagation Reveals Conformational Relationships among a Multitude of [PSI] Strains

Immense diversity of prion strains is observed, but its underlying mechanism is less clear. Three [PSI] prion strains—named VH, VK, and VL—were previously isolated in the wild-type yeast genetic background. Here we report the generation and characterization of eight new [PSI] isolates, obtained by p...

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Detalles Bibliográficos
Autores principales: Lin, Jia-Yu, Liao, Tzu-Ya, Lee, Han-Chung, King, Chih-Yen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183073/
https://www.ncbi.nlm.nih.gov/pubmed/21980301
http://dx.doi.org/10.1371/journal.pgen.1002297