Misregulation of Scm3p/HJURP Causes Chromosome Instability in Saccharomyces cerevisiae and Human Cells

The kinetochore (centromeric DNA and associated proteins) is a key determinant for high fidelity chromosome transmission. Evolutionarily conserved Scm3p is an essential component of centromeric chromatin and is required for assembly and function of kinetochores in humans, fission yeast, and budding...

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Detalles Bibliográficos
Autores principales: Mishra, Prashant K., Au, Wei-Chun, Choy, John S., Kuich, P. Henning, Baker, Richard E., Foltz, Daniel R., Basrai, Munira A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183075/
https://www.ncbi.nlm.nih.gov/pubmed/21980305
http://dx.doi.org/10.1371/journal.pgen.1002303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183075/
https://www.ncbi.nlm.nih.gov/pubmed/21980305
http://dx.doi.org/10.1371/journal.pgen.1002303

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