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Bmp and Nodal Independently Regulate lefty1 Expression to Maintain Unilateral Nodal Activity during Left-Right Axis Specification in Zebrafish

In vertebrates, left-right (LR) axis specification is determined by a ciliated structure in the posterior region of the embryo. Fluid flow in this ciliated structure is responsible for the induction of unilateral left-sided Nodal activity in the lateral plate mesoderm, which in turn regulates organ...

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Detalles Bibliográficos
Autores principales: Smith, Kelly A., Noël, Emily, Thurlings, Ingrid, Rehmann, Holger, Chocron, Sonja, Bakkers, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183088/
https://www.ncbi.nlm.nih.gov/pubmed/21980297
http://dx.doi.org/10.1371/journal.pgen.1002289