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Cell Type–Specific Transcriptome Analysis Reveals a Major Role for Zeb1 and miR-200b in Mouse Inner Ear Morphogenesis

Cellular heterogeneity hinders the extraction of functionally significant results and inference of regulatory networks from wide-scale expression profiles of complex mammalian organs. The mammalian inner ear consists of the auditory and vestibular systems that are each composed of hair cells, suppor...

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Detalles Bibliográficos
Autores principales: Hertzano, Ronna, Elkon, Ran, Kurima, Kiyoto, Morrisson, Annie, Chan, Siaw-Lin, Sallin, Michelle, Biedlingmaier, Andrew, Darling, Douglas S., Griffith, Andrew J., Eisenman, David J., Strome, Scott E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183091/
https://www.ncbi.nlm.nih.gov/pubmed/21980309
http://dx.doi.org/10.1371/journal.pgen.1002309