Presynaptic Regulation of Quantal Size: K(+)/H(+) Exchange Stimulates Glutamate Storage by Increasing Membrane Potential

The amount of neurotransmitter stored in a single synaptic vesicle can determine the size of the postsynaptic response, but the factors that regulate vesicle filling remain poorly understood. A proton electrochemical gradient (Δμ(H+)) generated by the vacuolar H(+)-ATPase drives the accumulation of...

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Detalles Bibliográficos
Autores principales: Goh, Germaine Y., Huang, Hai, Ullman, Julie, Borre, Lars, Hnasko, Thomas S., Trussell, Laurence O., Edwards, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183113/
https://www.ncbi.nlm.nih.gov/pubmed/21874016
http://dx.doi.org/10.1038/nn.2898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183113/
https://www.ncbi.nlm.nih.gov/pubmed/21874016
http://dx.doi.org/10.1038/nn.2898

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