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Presynaptic Regulation of Quantal Size: K(+)/H(+) Exchange Stimulates Glutamate Storage by Increasing Membrane Potential
The amount of neurotransmitter stored in a single synaptic vesicle can determine the size of the postsynaptic response, but the factors that regulate vesicle filling remain poorly understood. A proton electrochemical gradient (Δμ(H+)) generated by the vacuolar H(+)-ATPase drives the accumulation of...
Autores principales: | Goh, Germaine Y., Huang, Hai, Ullman, Julie, Borre, Lars, Hnasko, Thomas S., Trussell, Laurence O., Edwards, Robert H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183113/ https://www.ncbi.nlm.nih.gov/pubmed/21874016 http://dx.doi.org/10.1038/nn.2898 |
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