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Neuroprotective Potential of Biphalin, Multireceptor Opioid Peptide, Against Excitotoxic Injury in Hippocampal Organotypic Culture

Biphalin is a dimeric opioid peptide that exhibits affinity for three types of opioid receptors (MOP, DOP and KOP). Biphalin is undergoing intensive preclinical study. It was recognized that activation of δ-opioid receptor elicits neuroprotection against brain hypoxia and ischemia. We compare the ef...

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Detalles Bibliográficos
Autores principales: Kawalec, Maria, Kowalczyk, Joanna E., Beresewicz, Malgorzata, Lipkowski, Andrzej W., Zablocka, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183243/
https://www.ncbi.nlm.nih.gov/pubmed/21842273
http://dx.doi.org/10.1007/s11064-011-0568-1