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Ceruloplasmin Protects Against Rotenone-Induced Oxidative Stress and Neurotoxicity

To clarify the neuroprotective property of ceruloplasmin and the pathogenesis of aceruloplasminemia, we generated ceruloplasmin-deficient (CP (−/−)) mice on the C57BL/10 genetic background and further treated them with a mitochondrial complex I inhibitor, rotenone. There was no iron accumulation in...

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Detalles Bibliográficos
Autores principales: Hineno, Akiyo, Kaneko, Kazuma, Yoshida, Kunihiro, Ikeda, Shu-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183265/
https://www.ncbi.nlm.nih.gov/pubmed/21706374
http://dx.doi.org/10.1007/s11064-011-0537-8