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Ceruloplasmin Protects Against Rotenone-Induced Oxidative Stress and Neurotoxicity
To clarify the neuroprotective property of ceruloplasmin and the pathogenesis of aceruloplasminemia, we generated ceruloplasmin-deficient (CP (−/−)) mice on the C57BL/10 genetic background and further treated them with a mitochondrial complex I inhibitor, rotenone. There was no iron accumulation in...
Autores principales: | Hineno, Akiyo, Kaneko, Kazuma, Yoshida, Kunihiro, Ikeda, Shu-ichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183265/ https://www.ncbi.nlm.nih.gov/pubmed/21706374 http://dx.doi.org/10.1007/s11064-011-0537-8 |
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