Cargando…

Regulation of NF-κB activity by competition between RelA acetylation and ubiquitination

The NF-κB transcription factor plays essential roles in inflammation and oncogenesis. Its ubiquitous RelA subunit is regulated by several post-translational modifications (PTMs) including phosphorylation, ubiquitination, and acetylation. Ubiquitination promotes the termination of RelA-dependent tran...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Haiying, Wittwer, Tobias, Weber, Axel, Schneider, Heike, Moreno, Rita, Maine, Gabriel N., Kracht, Michael, Schmitz, M. Lienhard, Burstein, Ezra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183278/
https://www.ncbi.nlm.nih.gov/pubmed/21706061
http://dx.doi.org/10.1038/onc.2011.253