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Identification of Novel α-Synuclein Isoforms in Human Brain Tissue by using an Online NanoLC-ESI-FTICR-MS Method

Parkinson’s disease (PD) and Dementia with Lewy bodies (DLB) are neurodegenerative diseases that are characterized by intra-neuronal inclusions of Lewy bodies in distinct brain regions. These inclusions consist mainly of aggregated α-synuclein (α-syn) protein. The present study used immunoprecipitat...

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Detalles Bibliográficos
Autores principales: Öhrfelt, Annika, Zetterberg, Henrik, Andersson, Kerstin, Persson, Rita, Secic, Dzemila, Brinkmalm, Gunnar, Wallin, Anders, Mulugeta, Ezra, Francis, Paul T., Vanmechelen, Eugeen, Aarsland, Dag, Ballard, Clive, Blennow, Kaj, Westman-Brinkmalm, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183298/
https://www.ncbi.nlm.nih.gov/pubmed/21674238
http://dx.doi.org/10.1007/s11064-011-0527-x