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Differential Pharmacological Actions of Methadone and Buprenorphine in Human Embryonic Kidney 293 Cells Coexpressing Human μ-Opioid and Opioid Receptor-Like 1 Receptors

Methadone and buprenorphine are used in maintenance therapy for heroin addicts. In this study, we compared their effects on adenylate cyclase (AC) activity in human embryonic kidney (HEK) 293 cells stably overexpressing human μ-opioid receptor (MOR) and nociceptin/opioid receptor-like 1 receptor (OR...

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Detalles Bibliográficos
Autores principales: Lee, Cynthia Wei-Sheng, Yan, Jia-Ying, Chiang, Yao-Chang, Hung, Tsai-Wei, Wang, Hung-Li, Chiou, Lih-Chu, Ho, Ing-Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183316/
https://www.ncbi.nlm.nih.gov/pubmed/21671107
http://dx.doi.org/10.1007/s11064-011-0525-z