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Effect of doxycycline in patients of moderate to severe chronic obstructive pulmonary disease with stable symptoms
BACKGROUND: The protease-antiprotease hypothesis proposes that inflammatory cells and oxidative stress in chronic obstructive pulmonary disease (COPD) produce increased levels of proteolytic enzymes (neutrophil elastase, matrix metalloproteinases [MMP]) which contribute to destruction of parenchyma...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183640/ https://www.ncbi.nlm.nih.gov/pubmed/21977068 http://dx.doi.org/10.4103/1817-1737.84777 |