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Assessment of the role of paraoxonase gene polymorphism (Q192R) and paraoxonase activity in the susceptibility to atherosclerosis among lead-exposed workers

BACKGROUND AND OBJECTIVE: Lead exposure is a well known cause of cardiovascular damage, including atherosclerosis. Paraoxonase 1 (PON1), a high-density lipoprotein-associated antioxidant enzyme, is capable of hydrolyzing oxidized lipids and thus it protects against atherosclerosis. The mechanism by...

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Detalles Bibliográficos
Autores principales: Kamal, Manal, Fathy, Mona M., Taher, Eman, Hasan, Manal, Tolba, May
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183682/
https://www.ncbi.nlm.nih.gov/pubmed/21911985
http://dx.doi.org/10.4103/0256-4947.84625