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Isolation of a Human Anti-HIV gp41 Membrane Proximal Region Neutralizing Antibody by Antigen-Specific Single B Cell Sorting

Broadly neutralizing antibodies are not commonly produced in HIV-1 infected individuals nor by experimental HIV-1 vaccines. When these antibodies do occur, it is important to be able to isolate and characterize them to provide clues for vaccine design. CAP206 is a South African subtype C HIV-1-infec...

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Detalles Bibliográficos
Autores principales: Morris, Lynn, Chen, Xi, Alam, Munir, Tomaras, Georgia, Zhang, Ruijun, Marshall, Dawn J., Chen, Bing, Parks, Robert, Foulger, Andrew, Jaeger, Frederick, Donathan, Michele, Bilska, Mira, Gray, Elin S., Abdool Karim, Salim S., Kepler, Thomas B., Whitesides, John, Montefiori, David, Moody, M. Anthony, Liao, Hua-Xin, Haynes, Barton F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184076/
https://www.ncbi.nlm.nih.gov/pubmed/21980336
http://dx.doi.org/10.1371/journal.pone.0023532