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Transdifferentiation from cornea to lens in Xenopus laevis depends on BMP signalling and involves upregulation of Wnt signalling

BACKGROUND: Surgical removal of the lens from larval Xenopus laevis results in a rapid transdifferention of central corneal cells to form a new lens. The trigger for this process is understood to be an induction event arising from the unprecedented exposure of the cornea to the vitreous humour that...

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Detalles Bibliográficos
Autores principales: Day, Robert C, Beck, Caroline W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184090/
https://www.ncbi.nlm.nih.gov/pubmed/21896182
http://dx.doi.org/10.1186/1471-213X-11-54