Cargando…
Cytoplasmic p21 is a potential predictor for cisplatin sensitivity in ovarian cancer
BACKGROUND: P21((WAF1/Cip1) )binds to cyclin-dependent kinase complexes and inhibits their activities. It was originally described as an inhibitor of cancer cell proliferation. However, many recent studies have shown that p21 promotes tumor progression when accumulated in the cell cytoplasm. So far,...
Autores principales: | , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184122/ https://www.ncbi.nlm.nih.gov/pubmed/21933447 http://dx.doi.org/10.1186/1471-2407-11-399 |