Identification of a Conserved Anti-Apoptotic Protein That Modulates the Mitochondrial Apoptosis Pathway

Here we identified an evolutionarily highly conserved and ubiquitously expressed protein (C9orf82) that shows structural similarities to the death effector domain of apoptosis-related proteins. RNAi knockdown of C9orf82 induced apoptosis in A-549 and MCF7/casp3-10b lung and breast carcinoma cells, r...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Johansson, Elisabet, Miller, Marian L., Jänicke, Reiner U., Ferguson, Donald J., Plas, David, Meller, Jarek, Anderson, Marshall W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184134/
https://www.ncbi.nlm.nih.gov/pubmed/21980415
http://dx.doi.org/10.1371/journal.pone.0025284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184134/
https://www.ncbi.nlm.nih.gov/pubmed/21980415
http://dx.doi.org/10.1371/journal.pone.0025284

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