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Pol III binding in six mammalian genomes shows high conservation among amino acid isotypes, despite divergence in tRNA gene usage

RNA polymerase III (pol III) transcription of transfer RNA (tRNA) genes is essential for generating the tRNA adapter molecules that link genetic sequence and protein translation. By mapping pol III occupancy genome-wide in the livers of mouse, rat, human, macaque, dog and opossum, we found that pol...

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Detalles Bibliográficos
Autores principales: Kutter, Claudia, Brown, Gordon D., Gonçalves, Ângela, Wilson, Michael D., Watt, Stephen, Brazma, Alvis, White, Robert J., Odom, Duncan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184141/
https://www.ncbi.nlm.nih.gov/pubmed/21873999
http://dx.doi.org/10.1038/ng.906