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Insulin-Producing Cells Generated from Dedifferentiated Human Pancreatic Beta Cells Expanded In Vitro

BACKGROUND: Expansion of beta cells from the limited number of adult human islet donors is an attractive prospect for increasing cell availability for cell therapy of diabetes. However, attempts at expanding human islet cells in tissue culture result in loss of beta-cell phenotype. Using a lineage-t...

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Detalles Bibliográficos
Autores principales: Russ, Holger A., Sintov, Elad, Anker-Kitai, Leeat, Friedman, Orr, Lenz, Ayelet, Toren, Ginat, Farhy, Chen, Pasmanik-Chor, Metsada, Oron-Karni, Varda, Ravassard, Philippe, Efrat, Shimon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184150/
https://www.ncbi.nlm.nih.gov/pubmed/21984932
http://dx.doi.org/10.1371/journal.pone.0025566