Imaging Mass Spectrometry Reveals Elevated Nigral Levels of Dynorphin Neuropeptides in L-DOPA-Induced Dyskinesia in Rat Model of Parkinson's Disease

L-DOPA-induced dyskinesia is a troublesome complication of L-DOPA pharmacotherapy of Parkinson's disease and has been associated with disturbed brain opioid transmission. However, so far the results of clinical and preclinical studies on the effects of opioids agonists and antagonists have been...

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Detalles Bibliográficos
Autores principales: Ljungdahl, Anna, Hanrieder, Jörg, Fälth, Maria, Bergquist, Jonas, Andersson, Malin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184165/
https://www.ncbi.nlm.nih.gov/pubmed/21984936
http://dx.doi.org/10.1371/journal.pone.0025653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184165/
https://www.ncbi.nlm.nih.gov/pubmed/21984936
http://dx.doi.org/10.1371/journal.pone.0025653

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