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Cdk5 Is Required for Memory Function and Hippocampal Plasticity via the cAMP Signaling Pathway
Memory formation is modulated by pre- and post-synaptic signaling events in neurons. The neuronal protein kinase Cyclin-Dependent Kinase 5 (Cdk5) phosphorylates a variety of synaptic substrates and is implicated in memory formation. It has also been shown to play a role in homeostatic regulation of...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184170/ https://www.ncbi.nlm.nih.gov/pubmed/21984943 http://dx.doi.org/10.1371/journal.pone.0025735 |