Germline BAP1 mutations predispose to malignant mesothelioma

Because only a small fraction of asbestos-exposed individuals develop malignant mesothelioma(1), and because mesothelioma clustering is observed in some families(1), we searched for genetic predisposing factors. We discovered germline mutations in BAP1 (BRCA1-associated protein 1) in two families wi...

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Detalles Bibliográficos
Autores principales: Testa, Joseph R., Cheung, Mitchell, Pei, Jianming, Below, Jennifer E., Tan, Yinfei, Sementino, Eleonora, Cox, Nancy J., Dogan, A. Umran, Pass, Harvey I., Trusa, Sandra, Hesdorffer, Mary, Nasu, Masaki, Powers, Amy, Rivera, Zeyana, Comertpay, Sabahattin, Tanji, Mika, Gaudino, Giovanni, Yang, Haining, Carbone, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184199/
https://www.ncbi.nlm.nih.gov/pubmed/21874000
http://dx.doi.org/10.1038/ng.912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184199/
https://www.ncbi.nlm.nih.gov/pubmed/21874000
http://dx.doi.org/10.1038/ng.912

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