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Permanent relief from intermittent cold stress-induced fibromyalgia-like abnormal pain by repeated intrathecal administration of antidepressants

BACKGROUND: Fibromyalgia (FM) is characterized by chronic widespread pain, which is often refractory to conventional painkillers. Numerous clinical studies have demonstrated that antidepressants are effective in treating FM pain. We previously established a mouse model of FM-like pain, induced by in...

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Detalles Bibliográficos
Autores principales: Nishiyori, Michiko, Uchida, Hitoshi, Nagai, Jun, Araki, Kohei, Mukae, Takehiro, Kishioka, Shiroh, Ueda, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184270/
https://www.ncbi.nlm.nih.gov/pubmed/21933442
http://dx.doi.org/10.1186/1744-8069-7-69