A new class of IMP dehydrogenase with a role in self-resistance of mycophenolic acid producing fungi

BACKGROUND: Many secondary metabolites produced by filamentous fungi have potent biological activities, to which the producer organism must be resistant. An example of pharmaceutical interest is mycophenolic acid (MPA), an immunosuppressant molecule produced by several Penicillium species. The targe...

Descripción completa

Detalles Bibliográficos
Autores principales: Hansen, Bjarne G, Genee, Hans J, Kaas, Christian S, Nielsen, Jakob B, Regueira, Torsten B, Mortensen, Uffe H, Frisvad, Jens C, Patil, Kiran R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184278/
https://www.ncbi.nlm.nih.gov/pubmed/21923907
http://dx.doi.org/10.1186/1471-2180-11-202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184278/
https://www.ncbi.nlm.nih.gov/pubmed/21923907
http://dx.doi.org/10.1186/1471-2180-11-202

Ejemplares similares