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A new class of IMP dehydrogenase with a role in self-resistance of mycophenolic acid producing fungi
BACKGROUND: Many secondary metabolites produced by filamentous fungi have potent biological activities, to which the producer organism must be resistant. An example of pharmaceutical interest is mycophenolic acid (MPA), an immunosuppressant molecule produced by several Penicillium species. The targe...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184278/ https://www.ncbi.nlm.nih.gov/pubmed/21923907 http://dx.doi.org/10.1186/1471-2180-11-202 |