Hepatic Differentiation of Murine Disease-Specific Induced Pluripotent Stem Cells Allows Disease Modelling In Vitro

Direct reprogramming of somatic cells into pluripotent cells by retrovirus-mediated expression of OCT4, SOX2, KLF4, and C-MYC is a promising approach to derive disease-specific induced pluripotent stem cells (iPSCs). In this study, we focused on three murine models for metabolic liver disorders: the...

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Detalles Bibliográficos
Autores principales: Eggenschwiler, Reto, Loya, Komal, Sgodda, Malte, André, Francoise, Cantz, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184399/
https://www.ncbi.nlm.nih.gov/pubmed/21977043
http://dx.doi.org/10.4061/2011/924782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184399/
https://www.ncbi.nlm.nih.gov/pubmed/21977043
http://dx.doi.org/10.4061/2011/924782

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