Guards and Culprits in the Endoplasmic Reticulum: Glucolipotoxicity and β-Cell Failure in Type II Diabetes

The endoplasmic reticulum (ER) is a cellular organelle responsible for multiple important cellular functions including the biosynthesis and folding of newly synthesized proteins destined for secretion, such as insulin. The ER participates in all branches of metabolism, linking nutrient sensing to ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Karunakaran, Udayakumar, Kim, Han-Jong, Kim, Joon-Young, Lee, In-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184438/
https://www.ncbi.nlm.nih.gov/pubmed/21977023
http://dx.doi.org/10.1155/2012/639762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184438/
https://www.ncbi.nlm.nih.gov/pubmed/21977023
http://dx.doi.org/10.1155/2012/639762

Ejemplares similares