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From Understanding Cellular Function to Novel Drug Discovery: The Role of Planar Patch-Clamp Array Chip Technology

All excitable cell functions rely upon ion channels that are embedded in their plasma membrane. Perturbations of ion channel structure or function result in pathologies ranging from cardiac dysfunction to neurodegenerative disorders. Consequently, to understand the functions of excitable cells and t...

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Detalles Bibliográficos
Autores principales: Py, Christophe, Martina, Marzia, Diaz-Quijada, Gerardo A., Luk, Collin C., Martinez, Dolores, Denhoff, Mike W., Charrier, Anne, Comas, Tanya, Monette, Robert, Krantis, Anthony, Syed, Naweed I., Mealing, Geoffrey A. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184600/
https://www.ncbi.nlm.nih.gov/pubmed/22007170
http://dx.doi.org/10.3389/fphar.2011.00051