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Cyclic mechanical strain causes cAMP-response element binding protein activation by different pathways in cardiac fibroblasts

The transcription factor cAMP-response element binding protein (CREB) mediates the mechanical strain-induced gene expression in the heart. This study investigated which signaling pathways are involved in the straininduced CREB activation using cultured ventricular fibroblasts from adult rat hearts....

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Detalles Bibliográficos
Autores principales: Husse, Britta, Isenberg, Gerrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184707/
https://www.ncbi.nlm.nih.gov/pubmed/21977288
http://dx.doi.org/10.4081/hi.2010.e3