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Detecting Past Positive Selection through Ongoing Negative Selection
Detecting positive selection is a challenging task. We propose a method for detecting past positive selection through ongoing negative selection, based on comparison of the parameters of intraspecies polymorphism at functionally important and selectively neutral sites where a nucleotide substitution...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184776/ https://www.ncbi.nlm.nih.gov/pubmed/21859804 http://dx.doi.org/10.1093/gbe/evr086 |