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Detecting Past Positive Selection through Ongoing Negative Selection

Detecting positive selection is a challenging task. We propose a method for detecting past positive selection through ongoing negative selection, based on comparison of the parameters of intraspecies polymorphism at functionally important and selectively neutral sites where a nucleotide substitution...

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Detalles Bibliográficos
Autores principales: Bazykin, Georgii A., Kondrashov, Alexey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184776/
https://www.ncbi.nlm.nih.gov/pubmed/21859804
http://dx.doi.org/10.1093/gbe/evr086

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