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Second-generation aptamer-conjugated PSMA-targeted delivery system for prostate cancer therapy
BACKGROUND: miR-15a and miR-16-1 have been identified as tumor suppressor genes in prostate cancer, but their safe and effective delivery to target cells is key to the successful use of this therapeutic strategy. RNA aptamer A10 has been used as a ligand, targeting prostate cancer cells that express...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184934/ https://www.ncbi.nlm.nih.gov/pubmed/21980237 http://dx.doi.org/10.2147/IJN.S23747 |