Second-generation aptamer-conjugated PSMA-targeted delivery system for prostate cancer therapy

BACKGROUND: miR-15a and miR-16-1 have been identified as tumor suppressor genes in prostate cancer, but their safe and effective delivery to target cells is key to the successful use of this therapeutic strategy. RNA aptamer A10 has been used as a ligand, targeting prostate cancer cells that express...

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Detalles Bibliográficos
Autores principales: Wu, Xin, Ding, Baoyue, Gao, Jing, Wang, Huanyun, Fan, Wei, Wang, Xiang, Zhang, Wei, Wang, Xiaoyu, Ye, Lihua, Zhang, Min, Ding, Xueying, Liu, Jiyong, Zhu, Quangang, Gao, Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184934/
https://www.ncbi.nlm.nih.gov/pubmed/21980237
http://dx.doi.org/10.2147/IJN.S23747

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