Inhibition of PI3K Prevents the Proliferation and Differentiation of Human Lung Fibroblasts into Myofibroblasts: The Role of Class I P110 Isoforms

Idiopathic pulmonary fibrosis (IPF) is a progressive fibroproliferative disease characterized by an accumulation of fibroblasts and myofibroblasts in the alveolar wall. Even though the pathogenesis of this fatal disorder remains unclear, transforming growth factor-β (TGF-β)-induced differentiation a...

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Detalles Bibliográficos
Autores principales: Conte, Enrico, Fruciano, Mary, Fagone, Evelina, Gili, Elisa, Caraci, Filippo, Iemmolo, Maria, Crimi, Nunzio, Vancheri, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184941/
https://www.ncbi.nlm.nih.gov/pubmed/21984893
http://dx.doi.org/10.1371/journal.pone.0024663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184941/
https://www.ncbi.nlm.nih.gov/pubmed/21984893
http://dx.doi.org/10.1371/journal.pone.0024663

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