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How to Change the Oligomeric State of a Circular Protein Assembly: Switch from 11-Subunit to 12-Subunit TRAP Suggests a General Mechanism

BACKGROUND: Many critical cellular functions are performed by multisubunit circular protein oligomers whose internal geometry has evolved to meet functional requirements. The subunit number is arguably the most critical parameter of a circular protein assembly, affecting the internal and external di...

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Detalles Bibliográficos
Autores principales: Chen, Chao-Sheng, Smits, Callum, Dodson, Guy G., Shevtsov, Mikhail B., Merlino, Natalie, Gollnick, Paul, Antson, Alfred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184956/
https://www.ncbi.nlm.nih.gov/pubmed/21984911
http://dx.doi.org/10.1371/journal.pone.0025296