c-Rel Deficiency Increases Caspase-4 Expression and Leads to ER Stress and Necrosis in EBV-Transformed Cells

LMP1-mediated activation of nuclear factor of kappaB (NF-κB) is critical for the ligand independent proliferation and cell survival of in vitro EBV-transformed lymphoblastoid cell lines (LCLs). Previous experiments revealed that a majority of LMP1-dependent responses are regulated by NF-κB. However,...

Descripción completa

Detalles Bibliográficos
Autores principales: Valentín-Acevedo, Aníbal, Sinquett, Frank L., Covey, Lori R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184984/
https://www.ncbi.nlm.nih.gov/pubmed/21984918
http://dx.doi.org/10.1371/journal.pone.0025467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184984/
https://www.ncbi.nlm.nih.gov/pubmed/21984918
http://dx.doi.org/10.1371/journal.pone.0025467

Ejemplares similares