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Activation-Induced Cytidine Deaminase (AID)-Associated Multigene Signature to Assess Impact of AID in Etiology of Diseases with Inflammatory Component

Activation-induced cytidine deaminase (AID) is expressed in B cells within germinal centers and is critically involved in class switch recombination and somatic hypermutation of immunoglobulin loci. Functionally active AID can additionally be detected within ectopic follicular structures developed a...

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Detalles Bibliográficos
Autores principales: Mechtcheriakova, Diana, Sobanov, Yury, Holtappels, Gabriele, Bajna, Erika, Svoboda, Martin, Jaritz, Markus, Bachert, Claus, Jensen-Jarolim, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184987/
https://www.ncbi.nlm.nih.gov/pubmed/21984922
http://dx.doi.org/10.1371/journal.pone.0025611