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Impact of the Genome on the Epigenome Is Manifested in DNA Methylation Patterns of Imprinted Regions in Monozygotic and Dizygotic Twins

One of the best studied read-outs of epigenetic change is the differential expression of imprinted genes, controlled by differential methylation of imprinted control regions (ICRs). To address the impact of genotype on the epigenome, we performed a detailed study in 128 pairs of monozygotic (MZ) and...

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Detalles Bibliográficos
Autores principales: Coolen, Marcel W., Statham, Aaron L., Qu, Wenjia, Campbell, Megan J., Henders, Anjali K., Montgomery, Grant W., Martin, Nick G., Clark, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184992/
https://www.ncbi.nlm.nih.gov/pubmed/21991322
http://dx.doi.org/10.1371/journal.pone.0025590