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Engineering Bispecificity into a Single Albumin-Binding Domain

Bispecific antibodies as well as non-immunoglobulin based bispecific affinity proteins are considered to have a very high potential in future biotherapeutic applications. In this study, we report on a novel approach for generation of extremely small bispecific proteins comprised of only a single str...

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Detalles Bibliográficos
Autores principales: Nilvebrant, Johan, Alm, Tove, Hober, Sophia, Löfblom, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185003/
https://www.ncbi.nlm.nih.gov/pubmed/21991353
http://dx.doi.org/10.1371/journal.pone.0025791