Effect of Sulindac Sulfide on Metallohydrolases in the Human Colon Cancer Cell Line HT-29

Matrix metalloproteinase 7 (MMP7), a metallohydrolase involved in the development of several cancers, is downregulated in the Apc(Min/+) colon cancer mouse model following sulindac treatment. To determine whether this effect is relevant to the human condition, HT-29 human colon cancer cells were tre...

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Detalles Bibliográficos
Autores principales: Guillen-Ahlers, Hector, Tan, Jiangning, Castellino, Francis J., Ploplis, Victoria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185020/
https://www.ncbi.nlm.nih.gov/pubmed/21991341
http://dx.doi.org/10.1371/journal.pone.0025725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185020/
https://www.ncbi.nlm.nih.gov/pubmed/21991341
http://dx.doi.org/10.1371/journal.pone.0025725

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