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Effect of Sulindac Sulfide on Metallohydrolases in the Human Colon Cancer Cell Line HT-29
Matrix metalloproteinase 7 (MMP7), a metallohydrolase involved in the development of several cancers, is downregulated in the Apc(Min/+) colon cancer mouse model following sulindac treatment. To determine whether this effect is relevant to the human condition, HT-29 human colon cancer cells were tre...
Autores principales: | Guillen-Ahlers, Hector, Tan, Jiangning, Castellino, Francis J., Ploplis, Victoria A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185020/ https://www.ncbi.nlm.nih.gov/pubmed/21991341 http://dx.doi.org/10.1371/journal.pone.0025725 |
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