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Structural and functional roles of deamidation of N146 and/or truncation of NH(2)- or COOH-termini in human αB-crystallin

PURPOSE: The purpose of the study was to determine the relative effects of deamidation and/or truncation on the structural and functional properties of αB-crystallin. METHODS: Using wild-type (WT) αB-crystallin and the αB deamidated mutant (i.e., αB N146D), we generated NH(2)-terminal domain deleted...

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Detalles Bibliográficos
Autores principales: Asomugha, C.O., Gupta, R., Srivastava, O.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185027/
https://www.ncbi.nlm.nih.gov/pubmed/21976952