Leptin Reverts Pro-Apoptotic and Antiproliferative Effects of α-Linolenic Acids in BCR-ABL Positive Leukemic Cells: Involvement of PI3K Pathway

It is suspected that bone marrow (BM) microenvironmental factors may influence the evolution of chronic myeloid leukaemia (CML). In this study, we postulated that adipocytes and lipids could be involved in the progression of CML. To test this hypothesis, adipocytes were co-cultured with two BCR-ABL...

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Detalles Bibliográficos
Autores principales: Beaulieu, Aurore, Poncin, Géraldine, Belaid-Choucair, Zakia, Humblet, Chantal, Bogdanovic, Gordana, Lognay, Georges, Boniver, Jacques, Defresne, Marie-Paule
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185037/
https://www.ncbi.nlm.nih.gov/pubmed/21991326
http://dx.doi.org/10.1371/journal.pone.0025651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185037/
https://www.ncbi.nlm.nih.gov/pubmed/21991326
http://dx.doi.org/10.1371/journal.pone.0025651

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