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Inhibitory Activity of YKL-40 in Mammary Epithelial Cell Differentiation and Polarization Induced by Lactogenic Hormones: A Role in Mammary Tissue Involution

We previously reported that a secreted glycoprotein YKL-40 acts as an angiogenic factor to promote breast cancer angiogenesis. However, its functional role in normal mammary gland development is poorly understood. Here we investigated its biophysiological activity in mammary epithelial development a...

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Detalles Bibliográficos
Autores principales: Scully, Steve, Yan, Wei, Bentley, Brooke, Cao, Qing Jackie, Shao, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185048/
https://www.ncbi.nlm.nih.gov/pubmed/21991364
http://dx.doi.org/10.1371/journal.pone.0025819