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STAT3 Knockdown Reduces Pancreatic Cancer Cell Invasiveness and Matrix Metalloproteinase-7 Expression in Nude Mice

AIMS: Transducer and activator of transcription-3 (STAT3) plays an important role in tumor cell invasion and metastasis. The aim of the present study was to investigate the effects of STAT3 knockdown in nude mouse xenografts of pancreatic cancer cells and underlying gene expression. METHODS: A STAT3...

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Detalles Bibliográficos
Autores principales: Li, Hai dong, Huang, Chen, Huang, Ke jian, Wu, Wei dong, Jiang, Tao, Cao, Jun, Feng, Zhen zhong, Qiu, Zheng jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185063/
https://www.ncbi.nlm.nih.gov/pubmed/21991388
http://dx.doi.org/10.1371/journal.pone.0025941