Physicochemical interaction of antitumor acridinone derivatives with DNA in view of QSAR studies

The acridinone derivatives with antitumor activity and ability with respect to noncovalent DNA binding were investigated for their quantitative structure–activity relationships (QSAR). Multiple regression analysis was used to model relationships between molecular descriptors and antileukemia activit...

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Detalles Bibliográficos
Autores principales: Koba, Marcin, Bączek, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185225/
https://www.ncbi.nlm.nih.gov/pubmed/22003274
http://dx.doi.org/10.1007/s00044-010-9487-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185225/
https://www.ncbi.nlm.nih.gov/pubmed/22003274
http://dx.doi.org/10.1007/s00044-010-9487-y

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