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Physicochemical interaction of antitumor acridinone derivatives with DNA in view of QSAR studies
The acridinone derivatives with antitumor activity and ability with respect to noncovalent DNA binding were investigated for their quantitative structure–activity relationships (QSAR). Multiple regression analysis was used to model relationships between molecular descriptors and antileukemia activit...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer-Verlag
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185225/ https://www.ncbi.nlm.nih.gov/pubmed/22003274 http://dx.doi.org/10.1007/s00044-010-9487-y |