Gene expression study using real-time PCR identifies an NTR gene as a major marker of resistance to benznidazole in Trypanosoma cruzi

BACKGROUND: Chagas disease is a neglected illness, with limited treatments, caused by the parasite Trypanosoma cruzi. Two drugs are prescribed to treat the disease, nifurtimox and benznidazole, which have been previously reported to have limited efficacy and the appearance of resistance by T. cruzi....

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Detalles Bibliográficos
Autores principales: Mejía-Jaramillo, Ana M, Fernández, Geysson J, Palacio, Lina, Triana-Chávez, Omar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185274/
https://www.ncbi.nlm.nih.gov/pubmed/21892937
http://dx.doi.org/10.1186/1756-3305-4-169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185274/
https://www.ncbi.nlm.nih.gov/pubmed/21892937
http://dx.doi.org/10.1186/1756-3305-4-169

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